Cancer

A small-molecule drug inhibitor called vismodegib successfully treated a dire case of infiltrative basal cell carcinoma. According to the authors, this case qualifies as a first to report a complete remission for this subset of skin cancer. Basal cell carcinoma (BCC) is one of the most common types of skin cancer. For patients with locally
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Human papillomavirus (HPV) is responsible for causing cervical cancer in many women worldwide, and successful screening programs have been accredited with helping to increase the capacity to identify and treat precancerous and pre-invasive disease. Quantitative methylation of the POU4F3 gene biomarker is a valuable tool for high-grade CIN detection. Cervical cancer, caused by the human
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Cancer encompasses a range of diseases with varying mortality rates. A recent study has shown how cancer mortality rates have changed and influenced life expectancy over 30 years and have uncovered discrepancies in cancer control efforts between different populations. Cancer is predicted to become the primary cause of global morbidity and mortality, surpassing cardiovascular disease
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A recent study in JAMA Oncology compared the effectiveness of mammography alone vs. mammography in combination with MRI or ultrasonography in breast cancer screening. The results showed that combinatorial approaches could have a significant impact on detection rates and sensitivity for patients undergoing screening for recurrence. Breast cancer screening is an indispensable practice in the
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Long-term androgen deprivation therapy (ADT) in combination with abiraterone, a selective inhibitor of CYP17, an enzyme needed for androgen production, is associated with significantly higher rates of overall and failure-free survival than ADT alone among men with locally advanced or metastatic prostate cancer. Cancer of the prostate is the most prevalent disease in men, with
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The benefits of sentinel lymph node biopsy in treating skin cancer (melanoma) is well established; however, the value of lymph-node dissection, a procedure in which all nodes located nearby metastasis-positive sentinel nodes are surgically removed, remains controversial. Recently, a phase III clinical trial demonstrated that immediate completion lymph-node dissection is not associated with increased melanoma-specific
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