A study evaluating the risks and benefits of 3D mammogram screening aims to help physicians select the appropriate screening method for their patients. Breast cancer screening through mammography has allowed physicians to detect and track tumours before they become life-threatening, thus saving many lives. The type of screening used in practice will depend on how
In a national study, UK researchers investigated how prostate cancer patient choice, mobility, and hospital competition policies, impact hospital policies. Several countries including those in the United Kingdom have implemented policies which enable patients to choose a specific healthcare centre in a bid to improve the efficiency in the delivery of healthcare services. The result
Colon cancer is the third most common cancer worldwide. A group of researchers determine the link between antioxidants and digestive cancer risk. Colon cancer is the third most common cancer observed in both genders worldwide. Previous studies have proposed that antioxidants reduce the risk of development of different malignancies. However, there have only been few
An article published in the Gynecologic Oncology Research and Practice reviews the current medications available for treatment of ovarian cancer. Epithelial ovarian cancer is commonly diagnosed in its advanced stages. Although current management for ovarian cancer is effective in inducing a complete remission, a large proportion of patients eventually experience recurrence. In an article recently
With outstanding clinical results, a new cancer treatment attracting attention is cancer immunotherapy using bispecific antibodies. But is this treatment really the way forward? Tumour recurrence and the development of drug resistance are just two factors which contribute to the difficulties of curing cancer. Regardless of the advancements achieved in treating cancer, the development of
Researchers are investigating whether genetic engineering can restore the ability of natural killer cells to locate, enter and destroy certain tumours. Natural killer (NK) cells may be an important new anti-cancer treatment option. Natural killer cells, as a part of a healthy immune system are able to effectively kill a wide range of tumour cells.
Patient participation in clinical trials for cancer patients has been in decline. Researchers determine the barriers prohibiting participation. Randomized clinical trials are essential to testing whether a new treatment is better or worse than an existing one. Patients participating in clinical trials are typically randomly sorted into two groups: those receiving a new treatment under
A new study published in JAMA Surgery looked at whether individual surgeon opinions on mastectomy had a great influence on whether the patient underwent the surgery. In 2013, Angelina Jolie promoted prophylactic mastectomy, a breast removal surgery to reduce the risk of developing breast cancer. Prophylactic mastectomy in women who carry certain gene mutations, such
Researchers sought to characterize neurological disorders associated with anti-programmed death antibodies for the treatment of metastatic cancers. One method a tumour may escape destruction by the immune system is to affect the cells that would otherwise destroy it. For the body to distinguish its own normally-functioning cells from abnormal cells and invaders, normal cells display
Researchers studied whether nipple-sparing mastectomy was a safe surgical procedure for breast cancer prevention in women with BRCA gene mutations who are at high risk of developing breast cancer. There are many different risks for breast cancer, but one important factor is a family history of the disease. Researchers have discovered that in some families
In a recent study, researchers aim to identify what information is most important to pancreatic cancer patients following their diagnosis. While the prognosis for pancreatic cancer patients has been improving with time, the disease is still considered to be incurable. Moreover, the life expectancy and quality of life for people diagnosed depends heavily on the
Two trials studied the effects of hormone replacement therapy in post-menopausal women to determine any effects on all-cause mortality and mortality from heart disease or cancer. The United States National Institutes of Health launched the Women’s Health Initiative in 1991 to understand the causes of heart disease, breast and colorectal cancer, and osteoporotic fractures in
Researchers determine whether lenalidomide is an effective maintenance therapy for leukemia patients. The first-line treatment for patients diagnosed with chronic lymphocytic leukemia (CLL) is typically chemoimmunotherapy. Patients with a high risk of early disease progression are those with higher levels of residual disease after chemoimmunotherapy and/or those with specific genetic markers. For these patients, maintenance
Millions of people take low-dose aspirin to prevent heart attacks and strokes. Researchers determine whether a new use of low-dose aspirin can help in colorectal cancer prevention. Colorectal rectal is a very common cancer and the second most diagnosed cancer in Canada with roughly 27,000 new cases diagnosed annually.1 Follow-up studies in patients on low-dose
Naturally-occurring radon can be found at higher than recommended levels in some people’s homes. A recent US study examined a potential link between radon exposure and breast cancer. Breast cancer is the leading cause of cancer-related death among women worldwide. There are different types of breast tumors according to their responsiveness to various hormones and
A new meta-analysis examines the controversial relationship between protein intake from our diet and the risk of developing colorectal cancer. Colorectal cancer, which includes both colon and rectal cancer, is one of the most common types of cancers that are able to metastasize, which is when cancer travels to different sites in the body. This
This past August 2017 the US Food and Drug Administration made what many are calling a ‘historic action’ with the decision to approve the first gene therapy for leukemia in the US. Leukemia is a cancer of the blood cells. There are many different types of leukemia based on the type of blood cell affected
Advances in nanotechnology may soon give rise to an innovative way in the treatment of cancer: drilling through the membrane and destroying the cancer cells. The basic tenet of cancer treatment is its total eradication from the human body, but the aggressive and invasive nature of malignancies complicate and in many instances prevent this from
Personalized medicine is the future of cancer therapy. A recent report shows that one lab has successfully tested the zebrafish cancer response and its potential to be used to personalize patient treatment. Cancer is a heterogeneous disease. Not only are different types of cancers unique from one another, like brain cancer and breast cancer, but
A new study investigates a possible link between variants of the vitamin D receptor gene and the risk of developing nonmelanoma skin cancer. Nonmelanoma skin cancer refers to all forms of skin cancer that develops in the lower parts of the outer epidermis, including basal cells (basal cell carcinoma) and squamous cells (squamous cell carcinoma).
With millions of cancer-related ER visits per year, and cancer rates anticipated to double by 2040, healthcare facilities will need to thoughtfully prepare to maintain operational standards. Emergency departments are notoriously overburdened, resulting in huge inefficiencies. Most people have a personal story of waiting for hours at “emergency” clinics overwhelmed with people requiring immediate care.
A recently published study set out to discover whether an immune signature can be used to provide a reliable prognosis for patients with early-stage lung cancer. Of all lung cancer cases, 85% are attributable to non-small cell lung cancer (NSCLC), the leading cause of cancer deaths worldwide. Many patients with early-stage lung cancer do not
Durvalumab is one of a group of new cancer drugs called immune “checkpoint inhibitors”. It is undergoing clinical trials and the initial findings of its use in advanced bladder cancer have been reported in a recent study. The immune system is made up of organs, cells, and substances within the body which helps to protect
A recent study determines whether the prevalence of neuropathic pain in women following breast cancer treatment is higher compared with those in other cancer types. Neuropathic pain is pain that is caused by damaged or dysfunctional nerve cells, which results in pain signals being sent to the brain. It is associated with a host of
This is the first reported instance of restoration of hair color in response to anti-PD1/anti-PD-L1lung cancer treatment therapy. Programmed cell death protein 1 (PD-1) is a protein present on the surface of a number of cells of the immune system, such asCD4+ and CD8+ T cells, B cells, monocytes, natural killer cells, and dendritic cells.1 As
A recent study investigated gait characteristics in pediatric acute lymphoblastic leukemia (ALL) patients with chemotherapy-induced peripheral neuropathy (CIPN). Childhood acute lymphoblastic leukemia (ALL) is characterized by the excessive production of immature lymphocytes which are incapable of fighting infections. Although recent advances in chemotherapeutics have increased survival rates to almost 90%, these drugs are often accompanied
Olaparib (Lynparza) is a treatment for advanced ovarian cancer in patients carrying inherited mutations in the BRCA gene. A study compares olaparib with standard drugs for the treatment of metastatic breast cancer in patients with inherited BRCA mutation. Mutations in BRCA1 and BRCA2, the tumor suppressor genes that code for proteins involved in DNA
Comparing the effectiveness of an immunotherapy inhibitor, nivolumab, with platinum-based chemotherapy may help oncologists determine which drug is most beneficial as a first line treatment for patients with advanced or recurrent non-small-cell lung cancer. As its name suggests, platinum-based chemotherapy contains complexes of the metal platinum, which can bring along an entourage of symptoms.