Aging

A newly published study on the effects of a sedentary lifestyle has examined associations between physical activity and physical functioning in a geriatric population. Physical functioning is a key determinant of health for geriatric populations. The drop in the physical function has been found to be associated with disability and mortality. With the increasingly aging
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A recent study, published in BMC Geriatrics, investigates the association between total cholesterol and mortality in geriatric patients. It further explores whether this association can be altered with the use of cholesterol-lowering drugs. The association between high levels of total cholesterol and the increased risk of mortality in young and middle-aged people is well established.
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Researchers from East Carolina University performed a study using mice to look at the effects of exercise in reversing metabolic dysfunction in Alzheimer’s disease. Alzheimer’s disease (AD) is a neurological degenerative condition that leads to cognitive decline and memory loss. Alzheimer’s disease is strongly associated with aging and it is believed that over time, specific
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A recent study published in the British Medical Journal determines whether there is a correlation between the occurrence of rainfall and achy joints. It is widely believed that changes in the weather can contribute to the intensity of back and joint pain, especially for patients diagnosed with arthritis. Previous research on the topic, however, has
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Researchers use data from large-scale postmenopausal studies to determine whether long-term bisphosphonate use is a good solution for preventing osteoporotic fractures. Osteoporosis is frequently associated with an increased risk of fracture due to a reduction in bone mineral density. About half of women over 50 years old are expected to experience an osteoporotic fracture. Bisphosphonates,
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Researchers examined the relationship between gait stability and physical activity in older adults performing treadmill exercises. Walking is a good physical activity, and previous studies have found that it provides improved gait stability in the elderly. As published in the European Review of Aging and Physical Activity, researchers recently used treadmill exercises to evaluate the
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Researchers from Toronto reveal an innovative approach to study brain changes linked to working memory loss in people with Alzheimer’s disease. Alzheimer’s Disease and Dementia Dementia is a general term for the loss of memory and other cognitive skills. Unlike cognitive impairment associated with normal aging, the cognitive decline associated with dementia is serious enough
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A recent study investigated whether there is a link between consuming high glycemic foods and the accumulation of amyloid-β plaques in older adults. More than one in eight Americans aged over 65 years is affected by Alzheimer’s disease, the most common form of dementia. The hallmark characteristic of Alzheimer’s disease is the formation and accumulation
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A recent study investigated whether levels of brain atrophy in different subtypes of Alzheimer’s disease could be associated with different levels of education. Symptoms of brain atrophy, the shrinking of the brain which is caused by the loss of neurons, includes significant impairment to cognitive functions which can lead to Alzheimer’s disease dementia. Research has
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Researchers determine whether there is an association between aggressive treatment of hypertension and cognition function. Despite the relationship between hypertension and cognition being well established, recent concerns have arisen surrounding the treatment of hypertension. This concern is due to suspicions that more aggressive hypertension treatment, particularly in the elderly, may actually be linked to adverse
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In hopes to find a new treatment for Alzheimer’s, researchers determine if toxic tau tangles are the primary drivers responsible for the disease. The two pathological hallmarks of the devastating neurodegenerative disorder, Alzheimer’s disease, are amyloid plaques and tau protein tangles. Amyloid plaques and tau protein tangles are two brain abnormalities of Alzheimer’s disease. Amyloid
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A recent meta-analysis investigates whether sex, age, and a particular genotype are associated with a greater risk of developing Alzheimer’s disease. Alzheimer’s Disease (AD) is a chronic neurodegenerative condition, characterized by cognitive deficits in memory, thinking, and behaviour. Research has shown that different environmental, genetic, and socioeconomic cues can increase the risk of developing Alzheimer’s
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The relationship between memory and time has been studied extensively but is still poorly understood. A new study assessed memory and time deficits in Alzheimer’s disease (AD) patients in their home environments. It is widely accepted that as time passes, the ability to recall events and specific information declines. Episodic memory is the type of
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A recent analysis of geriatric patients hospitalized through emergency departments shows that proper geriatric assessments of older patients may reduce admission rates. A recent article published in Age and Ageing by the Oxford University Press reviewed the evidence behind performing comprehensive geriatric assessments (CGA) for more elderly patients that present at the emergency department. The
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In a recent study, researchers sought to identify proteins important for the anti-neural plasticity effects of histone deacetylase 2 (Hdac2) in Alzheimer’s disease. How Cells Control Gene Activity  Acetylation is one method by which cells control gene activity by the addition or removal of acetyl groups. Acetylation is performed by enzymes called acetyltransferases on histone
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Medication administration and management is a real problem in patients suffering from medical conditions associated with cognitive deficits. A recent study examined the experience of family members as they help take care of elder family members with Alzheimer’s disease. Compliance is an ongoing issue in medicine, particularly for elderly patients with medical conditions that cause
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Hydration health issues in the elderly have significant economic effects and while most elderly people recognize the importance of proper hydration, there may be limited health literacy including knowledge of signs and symptoms and health consequences of improper hydration. Dehydration is caused by excess fluid loss from the body and can lead to serious health
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In a 2017 study, researchers examined the relationship between rare gene variants and early-onset Alzheimer’s disease risk. Variants in a number of genes were identified, including PSD2, TCIRG1, and RIN3 – genes important to endolysosomal function. Mutations in a number of key genes have been implicated in the development of 5-10% of early-onset Alzheimer’s disease
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